Published in Cancer Weekly, February 8th, 2005
According to a study from the United States, "Altered p53 status is a frequent event in bladder cancer and reported to have prognostic significance.
"We studied the TP53 gene and its product in 76 patients affected with urinary bladder carcinomas by immunohistochemistry (mAb DO-7), polymerase chain reaction single-strand conformational polymorphism (exons 4-8) followed by direct sequencing of shifted bands, and loss of heterozygosity in 17p (p53CA). H-RAS mutations were also studied," wrote N. Erill and...
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