Kidney Cancer

CD10 expressed in some chromophobe renal cell carcinomas

Published in Cancer Weekly, February 8th, 2005

Contrary to conventional wisdom, CD10 is expressed in some chromophobe renal cell carcinomas.

"CD10 has been considered a useful marker in the diagnosis of renal carcinomas, because of its expression in clear cell and papillary renal cell carcinomas and its absence in chromophobe renal cell carcinomas," pathologists in Italy explained. "On the other hand, chromophobe renal cell carcinoma expresses parvalbumin, which is absent in clear cell and papillary renal cell carcinomas."

"To further address the relevance of these markers," G. Martignoni and colleagues at the University of Sassari evaluated "the expression of CD10 and parvalbumin in 42 samples...

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Source: Cancer Weekly (2005-02-08)

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