Published in Cancer Weekly, February 8th, 2005
Study 1: Psoralen derivatives and longwave ultraviolet irradiation is active against melanoma cells.
"Cutaneous malignant melanoma is a very serious form of skin cancer that arises from melanocytes. Currently there is no effective treatment for metastatic melanoma so intense clinical trials are evaluating new drugs for this human malignancy.
"Psoralens are a group of compounds that bind to DNA in rapidly dividing cells and with ultraviolet light in the A band (UVA) cause DNA crosslinking, thereby preventing cellular division. They are used in the...
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