Breast Cancer

IL-2 cultures fail to measure chromosomal radiosensitivity in study patients

Published in Cancer Weekly, February 8th, 2005

Researchers from Belgium reported that IL-2 cultures failed to measure chromosomal radiosensitivity in breast cancer patients that was observed in whole blood cultures from the same blood samples.

A. Vral and colleagues wrote in Mutagenesis, "Enhanced chromosomal radiosensitivity in breast cancer patients has been demonstrated in several studies. To investigate the chromosomal radiosensitivity of lymphocytes in breast cancer patients the G(2) and micronucleus (MN) assays are often used.

"In these assays blood samples are exposed to ionizing radiation and the number of radiation-induced micronuclei or chromatid breaks are scored."

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Source: Cancer Weekly (2005-02-08)

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