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Breast Cancer

MIB-1 and c-erbB-2 expression influence tumor cell morphology

Published in Cancer Weekly, February 8th, 2005

MIB-1 and c-erbB-2 expression influence the morphology of mammary gland tumor cells.

Researchers in Brazil conducted a study to determine "the expression of c-erbB-2 and MIB-1 and try to associate them with morphological features of the cell such as nuclear pleomorphism, mitotic count and histological grade in a series of 70 canine mammary gland tumors, 22 of them benign and 48 malignant."

"Tumors were collected at the Veterinary Hospital of UFMG (Brazil) and the Veterinary Faculty of Porto University (Portugal)," noted A.P. Dutra and colleagues at the Federal University of Minas Gerais. Tumor "c-erbB-2 expression was determined according to the...

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