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Breast Cancer

Prognostic value of intra-tumoral estradiol level determined

Published in Cancer Weekly, February 8th, 2005

The prognostic value of intra-tumor estradiol (E2) level has been determined in breast cancer patients.

Although the intra-tumoral E2 level "is thought to be more closely related to the E2-inducible events such as progesterone receptor (PR) induction and tumor growth than the serum E2 level, prognostic significance of the intra-tumoral E2 level in breast cancer patients has yet to be studied," according to oncologists in Japan.

In a study conducted by Y. Miyoshi and coauthors at Osaka University, "E2 level in tumor tissues obtained from 90 primary breast cancer patients was measured by the high-pressure liquid chromatography-radioimmunoassay method,"...

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