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Human Genome

Man and mouse share genome structure

Published in Cancer Weekly, February 15th, 2005

In the most detailed large-scale study to date of the proteins that package DNA, researchers have mapped a family of switches that turn genes on and off. Their findings may help scientists understand regulatory mechanisms underlying cancer and human development.

The research team includes first author Bradley Bernstein, recipient of a Howard Hughes Medical Institute (HHMI) physician postdoctoral fellowship who works in the Harvard University laboratory of HHMI investigator Stuart L. Schreiber. Other coauthors are from the Broad Institute of MIT and Harvard, and Affymetrix. Their findings were published in Cell.

"Every one of our cells has the...

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