Breast Cancer
Array CGH can identify genomic alterations in breast tumor subtypes
Published in Cancer Weekly, February 15th, 2005
In a recent study, researchers in the United States "performed high-resolution array comparative genomic hybridization with an array of 4,153 bacterial artificial chromosome clones to assess copy number changes in 44 archival breast cancers."
"The tumors were flow sorted to exclude non-tumor DNA and increase our ability to detect gene copy number changes," explained L.W.M. Loo and coauthors at the Fred Hutchinson Cancer Research Center in Seattle. "In these tumors, losses were more frequent than gains, and gains in 1q and loss in 16q were...
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Source: Cancer Weekly (2005-02-15)
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