Acute Myeloid Leukemia
Elevated AFlq gene expression is an independent adverse prognostic factor in AML
Published in Cancer Weekly, February 22nd, 2005
According to recent research from the United States, "The AF1q gene, a mixed-lineage leukemia fusion partner, is highly expressed in hematopoietic progenitor cells but has low expression in differentiated cells.
"We determined the expression of the AF1q gene by reverse transcriptase-polymerase chain reaction in 64 pediatric acute myeloid leukemia (AML) patients treated on Children's Cancer Group clinical trial CCG-2891 and correlated its expression level to clinical characteristics and outcome."
"AF1q expression in...
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Source: Cancer Weekly (2005-02-22)
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