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Cancer Vaccine

Dendritic cells and CD40-activated B cells in cancer immunotherapy reviewed

Published in Cancer Weekly, February 22nd, 2005

Researcher review the roles of dendritic cells and CD40-activated B cells in cancer immunotherapy in a recent issue of Trends in Immunology.

According to published research from Germany, "Despite the still poorly understood complexity of tumor-host immune interactions, the use of cellular vaccines (particularly dendritic cells) has made it possible to reliably generate tumor antigen-specific T cells, both in animal models and in humans. These encouraging preclinical results have led to a translation of these immunotherapeutic strategies into clinical trials. With numerous trials still underway, their general outcome has so far been disappointing, and the...

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