Acute Myeloid Leukemia
B-cell translocation gene 1 biomaker monitors acute myeloid leukemia remission
Published in Cancer Weekly, March 1st, 2005
According to a study from South Korea, "Acute myeloid leukemia (AML) is a biologically heterogeneous disease of the hematopoietic system characterized by a clonal accumulation of immature blast cells in bone marrow.
"We used a proteomic approach based on two-dimensional electrophoresis and mass spectrometry to search for biomarkers related to the complete remission (CR) state of AML patients."
"We detected one AML-related protein, which was identified as the B-cell translocation gene 1 (BTG1) protein that belongs to anti-proliferative...
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Source: Cancer Weekly (2005-03-01)
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