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Cancer Therapy

Reports add new data to cancer therapy research

Published in Cancer Weekly, March 15th, 2005

Data on cancer therapy are outlined in reports from the United States, Germany and Sweden.

Study 1: Angiogenesis inhibitors antagonize lymphoma proliferation.

"The role of angiogenesis in lymphoproliferative diseases is not well established. We demonstrate here that human lymphoma cells secrete vascular endothelial growth factor (VEGF) and express VEGF receptor 1 (VEGFR-1) and VEGFR-2. Proliferation of non-Hodgkin lymphoma (NHL) cells under serum-free conditions was enhanced by the addition of VEGF and was blocked by VEGFR-1-and VEGFR-2specific antibodies," researchers in the United States report.

"To differentiate between...

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