Published in Cancer Weekly, March 15th, 2005
"C. elegans embryonic cells have a common anterior/posterior (a/p) polarity that is apparent in the localization of the transcription factor POP-1. The level of nuclear POP-1 remains high in the anterior daughters of dividing cells but is lowered in the posterior daughters," wrote F.D. Park and colleagues, Fred Hutchinson Cancer Research Center.
"To generate POP-1 asymmetry, most early embryonic cells require contact with signaling cells that express the ligand...
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