Breast Cancer Vaccine
Anti-HER2 antibodies block HER2 phosphorylation and signaling
Published in Cancer Weekly, March 22nd, 2005
According to a study from the United States, "Immunologic targeting of the oncoprotein HER2/neu with monoclonal antibodies is an important component of current therapeutic strategies for patients with locally and systemically advanced breast cancer. Engineered antibodies targeting HER2 may have agonist or antagonist effects on HER2, but little is known about whether endogenous antibodies modulate HER2 activity. Vaccination of patients with HER2 peptides successfully induced antibodies in a minority of patients with HER2-expressing malignancy."
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Source: Cancer Weekly (2005-03-22)
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