Actinic Keratosis

Applying fluorouracil cream before cryosurgery reduces AK lesions, study shows

Published in Cancer Weekly, March 22nd, 2005

Conclusions of a 12-month clinical trial indicate that a 1-week course of treatment with the topical 0.5% fluorouracil cream Carac before cryosurgery is significantly more effective in reducing actinic keratosis (AK) lesions than cryosurgery alone.

The study, sponsored by Dermik Laboratories, is the first randomized, controlled trial to evaluate the long-term outcome of cryosurgery and the effect of a regimen using Carac before cryosurgery.

The 142 patients were randomly assigned to apply topical 0.5% fluorouracil cream or placebo once daily for 7 days to the face plus one or more investigator-designated areas, including the scalp, ears, neck and/or...

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Learn more about a six-week, no-risk free trial of Cancer Weekly

Source: Cancer Weekly (2005-03-22)

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