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Angiogenesis

Pharma company initiates phase II clinical study of lung cancer treatment

Published in Cancer Weekly, March 29th, 2005

Schering AG, Germany, (SCH; SHR) announced the initiation of recruitment for a phase II clinical trial of the experimental angiogenesis inhibitor PTK787/ZK 222584 (PTK/ZK) in the treatment of lung cancer.

The trial is designed to evaluate the efficacy of PTK/ZK as a second-line monotherapy in patients with stage IIIB/IV non-small cell lung cancer (NSCLC). The trial, known as the GOAL Study for Growth Arrest with Oral Anti-Angiogenesis in Lung Cancer, will be conducted in France and Germany at five different sites.

This study will include patients with stage IIIB/IV NSCLC who have relapsed or are refractory to first-line therapy.

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