Leukemia Vaccine
Leukemia vaccines may benefit from immune responses against Wilms tumor WT1
Published in Cancer Weekly, April 5th, 2005
According to a study from Japan, "The Wilms' tumor gene WT1 is highly expressed in leukemias and myelodysplastic syndrome (MDS), and WT1 expression levels increase along with the disease progression in chronic myeloid leukemia and MDS. We previously reported that IgM and IgG WT1 antibodies were detected with significantly higher detection rate and antibody titers in leukemias and MDS compared to those in healthy volunteers. In this study, whether IgG humoral immune responses against WT1 protein were Th1- or Th2-type were determined by...
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Source: Cancer Weekly (2005-04-05)
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