Diagnostics
UPAR may identify breast cancer patients with a risk for micrometastasis
Published in Cancer Weekly, April 12th, 2005
"Disseminated tumor cells (DTC) in bone marrow are independently related to poor outcome in patients with breast cancer. Phenotypic characterization of DTC may be useful to improve evaluation of the metastasizing potential of DTC and also to more accurately target aggressive tumor cells. DTC were screened in bone marrow aspirates from breast cancer patients by immunocytochemistry with an anticytokeratin (anti-CK) antibody (A45B/B3)," scientists in France report.
"Because the cell permeabilization and fixation required for intracellular CK staining is deleterious for mRNA, we...
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Source: Cancer Weekly (2005-04-12)
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