Immunology

Batracyclin derived muramyl dipeptides studied, biological activity reported

Published in Cancer Weekly, April 12th, 2005

Published research from Poland has described the biological activity of conjugates of muramyl dipeptides with batracyclin (BAT) derivatives.

"Antitumor activity of BAT, muramyldipeptide (MDP) and four immunomodulatory conjugates of BAT with MDP were evaluated in the study. The activity was assessed using viability tests performed in the cultures of tumor cell lines of different tissue origin such as WEHI 164 (fibrosarcoma), K562 (leukaemia), and Ab (melanoma), populations of immune cells isolated from peripheral blood, and the tumor cells mixed with immune cells," wrote P. Trzonkowski and colleagues, Medical Academy of Gdansk.

"An intensity of cell...

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Source: Cancer Weekly (2005-04-12)

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