Tumorigenesis

Tumor warning in blood explained

Published in Cancer Weekly, April 12th, 2005

Italian researchers have established a genetic mechanism for the long-sought-after link between cancer and blood clotting disorders, a result that might point to therapies for certain invasive cancers.

As early as 1865, doctors observed that certain blood clotting disorders serve as warning signs of occult malignancies (which lack easily detectable symptoms), but the molecules underlying this association were unknown.

Now Carla Boccaccio and her colleagues from the Institute for Cancer Research and Treatment, Torino, Italy reported in Nature that the human cancer-causing MET gene triggers both tumor development and blood clotting problems in...

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Source: Cancer Weekly (2005-04-12)

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