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Cancer Weekly

Susan Hasty, Publisher

Table of Contents . . . April 19th, 2005

Non-Subscriber - Summaries Only

Related Areas: Other Issues in Cancer Weekly | Other Publications

Cancer Genetics - Scientists uncover how BRCA2 regulates DNA repair

Liver Tumorigenesis - Liver tumorigenesis modulated in connexin32-deficient mice

Lung Cancer - Smoking implicated with ERCC1 polymorphisms and an increased risk of lung cancer

Melanoma - Chromosome locus identified as possible bearer of genes key to tumorigenesis

Mouse Skin Carcinogenesis - Antitumorigenic role for murine 8S-lipoxygenase in skin carcinogenesis

Acute Lymphocytic Leukemia - Clofarabine's interim results in leukemia reported at symposium

Acute Myeloid Leukemia - Criteria for defining complete remission re-evaluated

Addiction Medicine - Tumor necrosis factor antisense therapy fights alcoholic liver disease

Aging - p53 inhabited dual role as guardian and suppressor of longevity

Aging & Cancer Mortality - Variation in the human TP53 gene affected old-age survival and cancer mortality

Allergy & Immunology - Discovery of gene may lead to treatments for inflammatory diseases, cancer

Breast Cancer - Researchers provide details of new studies and findings in the area of breast cancer

Apoptosis - Homeobox Msx1 interacts with p53 and inhibits tumor growth via apoptosis

Asthma - Asthma deemed the ugly duckling of lung disease proteomics

Awards - Twenty-five scientists share $2.3 million in awards for prostate cancer research

Bacteriology - Data presented on Mycobacterial Cell Wall-DNA Complex

Birth Defects - Nitrofen associated with birth defects

Bone Cancer - Poly ADP-ribose polymerase inhibitors induced remodeling of chromatin

Enzymology - Studies advance knowledge in enzymology research

Bone Cancer - von Willebrand factor cultivates osteosarcoma metastasis

Brain Cancer - Imaging method gives early indication if brain cancer therapy is effective

Brain Lymphomas - PCNHSL and systemic lymphomas exhibited differential carcinogenesis

Breast Biopsy - Sublingual lorazepam reduces fainting risk during upright stereotactic biopsy

Breast Cancer - Almost half of women with early disease experience depression and anxiety

Breast Cancer - Antigen Express initiates clinical trials in Her-2/neu positive breast cancer

Hematology - Studies describe new findings in hematology research

Breast Cancer - Better outcome had with treatment by high-caseload surgeons

Breast Cancer - CYP1B1 and COMT polymorphisms not linked to increased risk

Breast Cancer - Cytotoxic activity of ent-16 beta-17 alpha-dihydroxykaurane on breast cancer

Breast Cancer - Data advance knowledge in breast cancer research

Breast Cancer - Goserelin and tamoxifen after chemo benefits younger node-positive patients

Breast Cancer - Her2(V655) genotype may be associated with disease progression in Korean women

Oncology - New research in the area of oncology detailed

Breast Cancer - Hyfrecator is effective treatment for radiation-induced telangiectasia

Breast Cancer - Identification of target genes directly regulated by SRC-3/AIB1 coactivator

Breast Cancer - Inactive human cathepsin D triggered fibroblast invasive growth

Breast Cancer - International breast cancer prevention study launches in U.S., Canada

Breast Cancer - KIT and EGFR overexpression correlated with invasive ductal breast cancer

Breast Cancer - New drugs contribute to neoadjuvant treatment of early breast cancer

Oncology - Recent findings illuminate research in oncology

Breast Cancer - Oral contraceptives may have protective effect

Breast Cancer - Pilot study to begin for new breast cancer blood test

Breast Cancer - Polymorphisms in DNA repair gene XRCC1 may increase genetic susceptibility

Breast Cancer - Polymorphisms in XRCC1 modified polycyclic aromatic hydrocarbon-DNA adducts

Breast Cancer - Randomized intervention study conducted on breast cancer survivors in Japan

Breast Cancer - Recommendations for breast cancer core biopsy listed

Oncology - Reports describe recent advances in oncology research

Breast Cancer - Reproductive risk factors similar in Western countries and Japan

Breast Cancer - Researcher wins Canadian Merck Frosst Prize for work on BRCA1 gene

Breast Cancer - Stroke risk higher in women with history of breast cancer

Breast Cancer - Study findings emphasize importance of early detection

Breast Cancer - The 3020insC allele of NOD2 associated with early-onset breast cancer

Oncology - Research in oncology provides new insights

Breast Cancer - Vinorelbine, epirubicin, 5-FU combo is manageable first-line chemotherapy

Breast Cancer - beta-Catenin signaling in basal mammary epithelial cells leads to hyperplasia

Breast Cancer Treatment - Cisplatin plus oral etoposide combination chemotherapy endorsed

Breast Cancer Treatment - Doxycycline enhanced tumor regression activity of cyclophosphamide

Breast Cancer Treatment - Radiotherapy for primary breast cancer increased risk of esophageal cancer

Breast Cancer Treatment - Treatment recommendations for octogenarian women with advanced breast cancer

Oncology - Researchers' data advance oncology research

Business & Finance - Therapeutics company reports financial results

Business Update - Automation solution provider announces organizations selected CrystalMation

Business Update - CT Laser Mammography system international distribution network expanded

Business Update - Enzon Pharmaceuticals terminates Marqibo agreement

Business Update - Medical products company retains investor relations firm

Cancer Cell Apoptosis - LDOC1, a novel MZF-1-interacting protein, induced apoptosis

Oncology - Studies advance knowledge in oncology research

Cancer Diagnostics - Tumor diagnosis using SPECT compared with F-18-FDG-PET

Cancer Drug Development - Role of noninvasive animal imaging in preclinical anticancer drug development

Cancer Drug Resistance - Recent advances in and therapeutic application of cell death signaling

Cancer Drugs - Cytotoxic and apoptotic activity of Triphala, an Indian herbal drug, reviewed

Cancer Drugs - Novel cytotoxic cyclic peptide, YM-216391, derived from Streptomyces nobilis

Cancer Drugs - Synthetic chalcones used as anti-inflammatory and cancer chemopreventive agents

Oncology - Studies describe new findings in oncology research

Cancer Gene Therapy - FGF20 targeted by beta-catenin and implicated in cancer development

Cancer Genes - Promoter of novel cancer-related gene 1A6/DRIM was identified and characterized

Cancer Genetics - Double-strand break repair gene variants not linked to breast or ovarian cancer

Cancer Metastases - Data support adjuvant use of ibandronate in metastatic bone disease

Cancer Pain Management - Short questionnaire developed to identify and treat physical and emotional pain

Cancer Prevention - Claudin-4 may mediate chemopreventive effects of NSAIDs

Cancer Prevention - Group endorses restriction of tanning bed use

Cancer Prevention - Oltipraz-regulated hepatocyte genes identified

Cancer Research - Armstrong seeks cyclists for Tour of Hope team to support cancer research

Cancer Research - Flavonoid in strawberries, other fruits, destroys cancer cells, study shows

Cancer Research - Pharma company announces preclinical experiments

Cancer Research - Synthesis and cytotoxic activity of 2-acyl-1H-indole-4,7-diones investigated

Cancer Risk Factors - Gender mix in twins and fetal growth studied; cancer risk assessed

Cancer Risk Factors - Genetics may explain a higher incidence of prostate cancer in Black men

Cancer Risk Factors - Hepatitis B and C coinfection heightens one's risk for developing liver cancer

Cancer Risk Factors - Viral hepatitis and aflatoxin biomarkers predict liver cancer risk

Cancer Support - Internet cancer support groups analyzed through a female perspective

Cancer Survival - Low tumor CD4+ T-lymphocyte infiltration associated with poor cancer survival

Cancer Survival - Modifications added to period analysis of cancer patient survival in datasets

Cancer Symptoms - Perceptions of cancer-related fatigue in children and young people surveyed

Cancer Therapy - Apoptotic effects of D-24851 on glioma cells characterized

Cancer Therapy - Approvable letter issued by U.S. FDA for Combidex

Cancer Therapy - Avian embryo models highlight the key steps of human tumor progression

Cancer Therapy - BAY 43-9006 delays disease progression in kidney cancer patients

Cancer Therapy - Cyclooxygenase-2 inhibitor battles metastatic breast cancer cells

Cancer Therapy - Early endostatin initiation hampers tumor seeding

Cancer Therapy - Forodesine clinical data presented at cancer meeting in Amsterdam

Cancer Therapy - IND submitted to U.S. FDA for HuC242-DM4 targeted anticancer compound

Cancer Therapy - Metal bonding domain of Fe(II)-bleomycin characterized

Cancer Therapy - Patient recruitment completed for phase IIb Pentrys trial

Cancer Therapy - Regulatory clearance granted for phase II trial of ADH-1 in Canada

Cancer Therapy - Research company presents preclinical data on anticancer activity in mice

Cancer Therapy - Studies describe new findings in cancer therapy research

Cancer Treatment - Grape seed proanthocyanidins induced apoptosis

Cancer Vaccines - Antibodies against cancer reviewed

Cancer Vaccines - Majority of women accept cervical cancer vaccine for self, children, study shows

Cancer Vaccines - Recent findings in cancer vaccines provide new insights

Cardiology - Aroylhydrazones merit investigation as protective agents against cardiotoxicity

Cell Biology - Natural tumor suppressor in body discovered

Cell Biology - Schwann cell and neuroblast interactions impact neuroblastoma biology

Cell Biology - Yeast finding links processes in heart disease and cancer

Cell Proliferation - Cell proliferation examined, role of dephosphorylated C/EBP alpha defined

Cell Signaling - RalA analyzed, nature of cell signaling interaction clarified

Central Nervous System Cancer - Treatment strategies for high-risk medulloblastoma and neuroectodermal tumors

Cervical Cancer - Adenocarcinoma in situ factors analyzed in hysterectomy specimens

Cervical Cancer - Lymphotoxin-alpha polymorphism and risk of cervical cancer in Japan examined

Cervical Cancer - Recent findings in cervical cancer provide new insights

Cervical Cancer - Strong proapoptotic protein expression a marker of poor radiotherapy outcome

Chronic Myeloid Leukemia -  IFITM1 expression has prognostic value

Clinical Oncology - Protocols for managing chemotherapy-induced neutropenia in clinical oncology

Clinical Trials - Initial data from clinical trial of anticancer agent in leukemia repored

Collaborations - Celgene to co-develop tubulin inhibitor cancer drugs

Collaborations - Research collaboration with International AIDS Vaccine Initiative announced

Colon Cancer - Company announces import approval for Elplat (oxaliplatin) in Japan

Colon Cancer - Pharma company gives results of investigational drug study in colon cancer

Colon Cancer - Primary care office strategies may increase colon cancer screening

Colon Cancer - Report: At-risk women still not heeding real threat of colon cancer

Colon Cancer - Trial of colon cancer treatment completes patient enrollment

Colon Cancer - Wnt/beta-catenin signaling pathway targeted PPAR-gamma activity in colon cancer

Colon Cancer Chemotherapy - CF101 enhanced chemotherapeutic effect of 5-fluorouracil in colon cancer

Colon Cancer Diagnostics - Integrin beta 6 implicated as novel prognostic indicator of colon carcinoma

Colon Cancer Prevention - Green vegetables may decrease colon cancer risk

Colorectal Cancer - African American women urged to heed screening guidelines

Colorectal Cancer - Cytomegalovirus not associated with colorectal tumorigenesis

Colorectal Cancer - Pharmacokinetics of 99mTc-labeled antibody in cancer patients reported

Colorectal Cancer - States failing to require insurance coverage of colorectal cancer screening

Colorectal Cancer Therapy - Hepatic arterial infusion not advised after resection of colorectal cancer

Dermatology - Recent findings illuminate research in dermatology

Diagnostics - Paramagnetic particles let magnetic resonance images depict tumor angiogenesis

Diagnostics - Researchers' data advance diagnostics research

Diagnostics Imaging - Research add new data to diagnostics imaging body of knowledge

Diet & Nutrition - Components in grapes inhibit enzyme key to proliferation of cancer cells

Diet & Nutrition - Compound in broccoli sprouts found to be disease fighter

Drug Development - Antiangiogenic therapy may help patients with Langerhans cell histiocytosis

Drug Development - Aspirin-derived cobalt-alkyne complexes have antitumor, anti-COX activity

Drug Development - Assay kit for kinase and phosphatase development introduced

Drug Development - Degarelix, a GnRH receptor, shows immediate onset of action, sustained activity

Drug Development - Glioma invasion genes function differentially in the brain and in vitro

Drug Development - Humanized immunoenzyme targets B-cell lymphoma

Drug Development - Novel indolylquinols have significant antitumor activity

Drug Development - Silibinin may repair diseases linked to pathological angiogenesis

Drug Discovery - Companies enter agreement for joint development of cancer therapies

Endocrinology - Deficiency of growth hormone and IGF-1 reduces cancer and kidney disease

Endocrinology - New data illuminates research in endocrinology

Endocrinology - Putative tumor suppressor DMBT1 is estrogen-regulated in uterus

Endocrinology - Supplemental DHEA may influence prostate health

Endometrial Cancer - Endometrial cancer in African-American women is more aggressive, studies show

Environmental Health - Mechanism of dicyclanil-induced hepatocarcinogenesis determined

Enzymology - Inducible caspase-9 disrupts neovascular growth after adenoviral delivery

Enzymology - Plasminogen activator inhibitor-1 boosts skin cancer progression

Enzymology - Reports advance knowledge in enzymology research

Epstein-Barr Virus - Researchers map role of common virus in cancer

Esophageal Cancer - HGF receptor c-Met overexpressed in esophageal adenocarcinoma

Esophageal Cancer - Human papillomavirus infection linked to Egyptian esophageal carcinoma

Esophageal Cancer - p53 gene mutation and HPV infection in esophageal cancer from 3 areas in India

Esophageal Candidiasis - Antifungal product for prophylaxis of Candida receives FDA approval

Eye Melanoma - Medium-sized juxtapapillary melanoma treated with external Co-60 photon therapy

Finance - Biology simulation company announces financial results

Finance - Cancer-focused pharmaceutical company reports Q4, full year 2004 results

Finance - Diagnostic tests provider announces 51% increase in product sales

Finance - Europe faces brain drain unless it doubles amount spent on cancer research

Finance - New debt securities issued by health-care services network

Gangrene - Pyoderma gangrenosum is treated successfully with infliximab

Gastric Cancer - Cyclin E overexpression with p53 expression may indicate poor prognosis

Gastric Cancer - Developments from Japan in chemotherapy for advanced gastric cancer revealed

Gastric Cancer - EPHA2/EFNA1 expressed in human gastric cancer

Gastric Cancer - Genetic polymorphisms increased risk of precancerous gastric lesions in Chinese

Gastric Cancer - Salt, salted food intake, and risk of gastric cancer linked

Gastroenterology - Intraperitoneal antisense K-ras RNA suppresses pancreatic cancer dissemination

Gastroenterology - Reports describe recent advances in gastroenterology research

Gastrointestinal Surgery - Modified stapling technique improves outcome of distal gastrectomy

Gene Research - BRCA2 knock-down exposes its potential to control alternate mechanisms

Gene Research - Doublecortin gene is a molecular marker for neuroblastoma residual disease

Genetic Disorders - STR replacements in UTRs and introns associated with gene expression and disease

Genetic Disorders - Uncoupling protein gene expression controlled by more than just hyperlipemia

Glioblastoma - Integrated DNA- and mRNA-based tumor profiles reveal novel subtypes

Glioblastoma Multiforme - Recombinant targeted toxin TP-38 can produce sustained response

Glioma Therapy - Rottlerin sensitizes glioma cells to TRAIL-induced apoptosis

Glioma Therapy - Sequential high-dose chemotherapy suitable for pediatric patients

Gynecology - Estrogen metabolism genes shape endometrial cancer susceptibility

HIV/AIDS Research - First pharmacokinetic results announced for PPL-100 protease inhibitor

HIV/AIDS Services - Partnership addresses needs of women and families affected by HIV/AIDS

HIV/AIDS Vaccines - Diagnostics products company provides China project update and summary

HIV/AIDS Vaccines - Stanford study finds HIV drug resistance assay superior to Virco's Antivirogram

Head & Neck Cancer - Alcohol and tobacco use increased risk of head and neck cancers

Head & Neck Cancer - Retinol-binding proteins silenced in nasopharyngeal carcinoma

Head & Neck Cancer - TAP1 and TAP2 allele frequencies analyzed in a SNaPshot

Head and Neck Cancer - Researchers' data advance head and neck cancer research

Health Promotion - Alternative channels provide information to cancer patients

Hematology - Arsenic trioxide-induced genetic changes cause multiple myeloma drug resistance

Hematology - B-cell lymphomas respond differentially to CpG oligodeoxynucleotides

Hematology - Reports describe recent advances in hematology research

Human Papillomavirus - PreTect HPV-Proofer for HPV E6/E7 mRNA detection gets thumbs up

Imaging - Swedish hospitals in Kalmar, Oskarshamn, Vostervik to get mammography systems

Imaging - Winthrop-University Hospital to install clinical IT and imaging technologies

Immunology - Cytokines and types of inflammatory cells expressed differently in HPV and HIV

Immunology - Scientists shed new light on role of natural killer T cells in fighting disease

Information Technology - Children's hospital uses predictive analytics to differentiate brain tumor types

Intercellular Peptides - Intercellular peptide transfer analyzed, cross-presentation documented

Leukemia - Genetically modified natural killer immune cells attack, kill leukemia cells

Leukemia Tumorigenesis - Evi3 expression in tumors altered level of EBF target genes in leukemia

Lipoatrophy - Promising results reported for HIV patients suffering from facial wasting

Lung Cancer - Is late diagnosis of lung cancer inevitable?

Lung Cancer - Luteolin-induced DNA damage led to lung squamous carcinoma CH27 cell apoptosis

Lung Cancer - New lung cancer medicine receives Swiss approval

Lung Cancer Therapy - Potent CDC25 inhibitors synthesized

Lung Cancer Treatment - Effects of gemcitabine and topotecan in human non-small cell lung cancer cells

Lymphoma - Histone deacetylase inhibitors decreased proliferation of human lymphoid cancer

Lymphoma - Truncated ALK associated with anaplastic lymphoma

Medical Devices - U.S. FDA grants clearance for treatment table with 550-pound load capacity

Medulloblastoma Therapy - Cranial irradiation linked to impaired white matter development in children

Melanoma - Protective effect of quercetin and luteolin in melanoma HMB-2 cells reviewed

Melanoma - Rate of deadly skin cancer set to triple

Melanoma Chemotherapy - Polysaccharides isolated from Phellinus gilvus inhibited melanoma

Melanoma Vaccines - Data advance knowledge in melanoma vaccines research

Mergers & Acquisitions - Acquisition of Research Diagnostics Inc by biotech company completed

Mergers & Acquisitions - Siemens to acquire imaging company with focus on PET, other imaging technologies

Mesothelioma - Podoplanin used as a marker for mesothelioma

Metastasis - SHP-2 promoted migration and metastasis of cancer cells

Muscle Degradation - NF-kappa B analyzed, effect on skeletal muscle protein degradation defined

Myelodysplastic Syndrome - Darbepoetin alpha suitable for anemia treatment in low-intermediate risk MDS

Myeloma - U.S. DOD awards $1.6 million contract to develop bone-targeting nanocapsules

Natural Products -  Boerhaavia diffusa extract curbs experimental melanoma metastasis

Natural Products - Cheongyeolsaseuptang treated rheumatoid arthritis

Neurocytoma - Optimal treatment for well-differentiated neurocytoma elucidated

Neuroscience - Virus-mediated endostatin gene transfer may cure malignant brain tumors

Non-Hodgkin Lymphoma - NAT and GST polymorphisms don't appear linked to NHL

Non-Small Cell Lung Cancer - Phase III study of XYOTAX results reported

Oncogenesis - New findings in the area of oncogenesis described

Oncology - Adolescents' experiences with cancer surveyed

Oncology - Antibody to podoplanin differentiates tumor-associated lymphangiogenesis

Oncology - Cellular stress factors propel the angiogenic switch in tumors

Oncology - Distinct cytogenetic factors guide thymic neuroendocrine tumor formation

Oncology - Environmental factors modify genetic susceptibility to primary liver cancer

Oncology - Findings describe new data in oncology research

Oncology - Fractionated dosage protocol can promote photodamage to neoplastic tissue

Oncology - Livin/ML-IAP shows promise as target antigen for lung cancer vaccine

Oncology - Metastatic breast cancer cells need intranuclear Runx2 for osteolysis

Oncology - NF-kappaB and IkappaB proteins associated with cancer and inflammation

Oncology - Nerve growth factor modulates cellular interactions in primary liver cancer

Oncology - New hypothesis on how high disease burden may explain low cancer burden

Oncology - Recombinant alpha 2(IV)NC1 domain blocks angiogenesis and tumor proliferation

Oncology - Retroviral insertional mutagenesis divulges the complexities of carcinogenesis

Oncology - Survivin may be suited for tumor-specific gene promotion in melanoma

Oncology - Topical ALA-photodynamic therapy is an effective treatment for Paget disease

Oncology - Transgenic mice show interleukin-6 supports melanoma growth and progression

Oncolysis - Microarray explores adenovirus-mediated E2F-1-induced apoptosis

Oral Healthcare - Operational research and efforts on oral health of older people encouraged

Osteopontin - Osteopontin autocrine secretion degrades I kappa B in Bcr-Abl-expressing cells

Ovarian Cancer - BRCA1 mutation acts through indirect, biochemical route

Ovarian Cancer - Cell surface carbohydrates involved in biological properties of cancer cells

Ovarian Cancer - Company initiates phase III trial of XYOTAX in ovarian cancer

Ovarian Cancer - Protective effects of anovulation factors persist from pre- to postmenopause

Ovarian Cancer - Researchers evaluating investigational therapy for ovarian cancer

Pain Management - Controlled sedation for the terminally ill explored in journal

Pancreatic Cancer - Cancer developed in remnant pancreas after pancreaticoduodenectomy

Pancreatic Cancer - Expression patterns of claudin-1 and claudin-4 in pancreatic tumors discussed

Pancreatic Cancer - Gene expression in pancreatic intraepithelial neoplasia characterized

Pancreatic Cancer - K-ras mutations tied pancreas cancer to adenocarcinoma and chronic pancreatitis

Patents - Biotechnology company receives patent for antibodies to cancer protein

Patents - European, Canadian allowances granted for anticancer drug in phase 2 trials

Pediatric Cancer Therapy - Rasburicase effective for treatment of cancer-related hyperuricemia

Pediatric Cancer Treatment - Cancer treatment for adolescents needed improvement

Pediatric Lymphoma - Genes cooperate to provoke immune system cancer B-cell lymphomas, study shows

Pediatric Oncology - Adenovirus hepatitis is fatal to children who receive chemotherapy for leukemia

Pediatric Sarcoma - Chemosensitivity in pediatric dermatofibrosarcoma protuberans described

Peripheral Arterial Disease - First drug-eluting stent implant for leg artery blockage performed at Stanford

Peripheral Nerve Sheath Tumors - Expression patterns of cell cycle components in MPNSTs detailed

Personnel - Diagnostics company names special advisor for molecular pathology

Personnel - Madhusudan V. Peshwa, PhD, named VP, R&D by clinical stage therapeutics company

Phosphatase - Molecular basis found for TPR domain-mediated regulation of protein phosphatase

Pituitary Cancer - Diagnosis and management of pituitary cancer reported

Pneumocystis Infection -  Pneumocystis outbreak transmitted within pediatric transplant unit

Polycythemia Vera - Cause of blood disorder found

Product Licensing - Company licenses compounds for oral diseases to Pacgen

Product Licensing - Swiss pharma, CSC announce ALOXI license agreement for Central, Eastern Europe

Prostate Cancer - Cultural and social factors influence prostate cancer treatment

Prostate Cancer - Hormonal treatment improves survival in high-risk patients

Prostate Cancer - Radiation therapy for prostate cancer nearly doubles risk for rectal cancer

Prostatic Hyperplasia - Biopharma company reports drug for benign prostatic hyperplasia holds promise

Protein Precursor - Presenilin attenuated receptor-mediated signaling and synaptic function

Proteomics - Findings in proteomics provide new insights

Quality of Life - Impact of age on quality of life in patients with rectal cancer reviewed

Sarcoma - Lack of clinical trial participation may contribute to lower survival rates

Schwannomas - Apoptosis rates reduced in human schwannomas

Sciatic Nerve - Cuff electrode implantation linked to upregulation of TNF-alpha and TGF-beta1

Skin Cancer - NF-kappa-B/Egr-1/Gadd45 activated upon UVB irradiation to mediate cell death

Skin Cancer - Perceptions and behaviors of Danish and American teens regarding skin cancer

Skin Cancer Prevention - Behaviors and motives that Dutch adolescents employed to prevent skin cancer

Soft Tissue Cancer - Case of giant retroperitoneal liposarcoma reported

Soft Tissue Cancer - Case of sarcomatoid carcinoma of renal pelvis with giant cell tumors reported

Stem Cell Research - SCL enhancer directs oncogenic fusion genes into stem cells

Stem Cell Transplantation - RT-PCR enables pre-emptive management of EBV reactivation after ASCT

Stem Cell Transplantation - cDNA library identifies HLA class II-restricted peptides recognized by CD4 cells

Stomach & Colon Cancer - Foxl1 implicated in carcinogenesis of stomach and colon cancers

Stomach & Intestinal Cancer - Biliary neoplastic obstruction managed with two implanted metallic stents

Stomach Cancer - Bile acids described as carcinogens in human gastrointestinal cancers

Thrombophilia & Cancer - Condition of thrombophilia in cancer explored

Thyroid Cancer - Biological impact of thyroid capsular inflammation discussed

Thyroid Cancer - Cancerous or harmless? Three genes might tell the tale

Thyroid Cancer Treatment - Surgical treatment of Hurthle cell tumors of the thyroid outlined

Tobacco Use - CYP2S1 not involved in activation of cigarette smoke carcinogens

Tobacco Use - Increased levels of metallothionein found in placenta of smokers

Tobacco Use - Smokers believe medicinal nicotine products may be harmful, study shows

Tuberculosis Treatment - Melatonin prevents free radical/MADD metabolic profiles induced by anti-TB drugs

Tumor Suppressors - Ubiquitin-independent proteasomal degradation of tumor suppressors reviewed

Tumorigenesis - Loss of translational control and development of human disease linked to mTOR

Tumorigenesis - Skp2 inhibited FOX01 in tumor suppression through ubiquitin-mediated degradation

Tumors - HER-2/neu overexpression drives tumor proliferation but not vascularization

Tumors - Tumor suppressor merlin studied, nucleocytoplasmic shuttling clarified

Urinary Tract Cancer - Papillary adenocarcinoma successfully treated by chemotherapy and surgery.

Urologic Diseases - Proteomic techniques revealed urologic diseases

Urology - Findings describe new data in urology research

Urothelial Carcinoma - Gemcitabine and docetaxel chemotherapy tried for advanced urothelial carcinoma

Vector Development - Pyridinium cationic lipids are well-suited for non-viral gene delivery

Virology - Cellular gene regulation by viral vectors raises quality control concerns

Virology - Human herpesvirus 8 developed mechanism to modulate antiviral response

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