Drug Development
Glioma invasion genes function differentially in the brain and in vitro
Published in Cancer Weekly, April 19th, 2005
According to recent research published in the journal Brain Pathology, "identification of genes mediating glioma invasion promotes the understanding of glia motility and might result in biologically based therapeutic approaches. Most experimental studies have been performed in vitro, although glial cells typically undergo marked phenotypic change following placement into cell culture."
"To evaluate migration mechanisms operating in vitro versus in vivo, we used C6 rat glioblastoma cells for selecting highly migratory cells in a monolayer migration assay as well as in...
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Source: Cancer Weekly (2005-04-19)
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