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Immunology

Scientists shed new light on role of natural killer T cells in fighting disease

Published in Cancer Weekly, April 19th, 2005

Researchers at the La Jolla Institute for Allergy & Immunology (LIAI) have identified the bacteria Sphingomonas as containing a glycolipid which naturally triggers an immune response from the body's natural killer (NK) T cells.

The finding sheds some light on the powerful, but little understood, workings of the NK T cells and will help scientists explore their possible use in fighting tumors and dangerous disease-causing bacteria.

In a paper, "Recognition of bacterial glycosphingolipids by natural killer T cells," published March 24 in the journal Nature, Mitchell Kronenberg, PhD, and an international team of scientists working at the...

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