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Brain Lymphomas
PCNHSL and systemic lymphomas exhibited differential carcinogenesis
April 19th, 2005
Researchers suggested that primary central nervous system lymphomas (PCNHSL) and systemic lymphomas exhibited differential carcinogenesis. "Ten PCNSL brain lymphomas were examined for p14 gene exon 1beta deletion, mutation and methylation by Southern blot analysis, nucleotide analysis of polymerase chain reaction clones and Southern blot-based methylation assay," scientists writing in the journal Cancer Science reported. "In Southern blot analysis, from the signal densities of the hybridized bands and their similarities to those of exons 2 and 3 in our previous quantitative study, we found that exon 1beta was homozygously deleted in 4 cases,...
Source: Cancer Weekly (2005-04-19)
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