Cancer Weekly
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Melanoma
Chromosome locus identified as possible bearer of genes key to tumorigenesis
April 19th, 2005
Pathologists have identified a chromosomal locus they suspect may bear genes key to metastatic melanoma tumorigenesis involving the breast. "Malignant melanoma (MM), the most common metastatic solid tumor to involve the breast, may present as a diagnostic problem, frequently requiring the use of ancillary studies for accurate diagnosis. The implication of hormonal interplay is strong since metastatic MM to the breast is seen nearly always in women. However, the role of hormonal status as a predisposing factor in the development of this entity is largely unresolved," wrote M.W. Beaty and colleagues, U.S. National Institutes of Health, Pathology Laboratory. ...
Source: Cancer Weekly (2005-04-19)
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