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Cancer Weekly

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Breast Cancer



Vinorelbine, epirubicin, 5-FU combo is manageable first-line chemotherapy



April 19th, 2005

Researchers in Italy report that continuous infusion with combined vinorelbine, epirubicin, and 5-fluorouracil is "an active and manageable first-line regimen for metastatic breast cancer patients."

"We investigated the activity and toxicity of a combination of vinorelbine 25 mg/m2 on days 1 and 15; epirubicin 25 mg/m2 on days 1, 8, 15; and 5-fluorouracil continuous infusion at 200 mg/m2 every day, administered as first-line chemotherapy in anthracycline-naive metastatic breast cancer patients. Fifty-three patients entered the study. Cycles were repeated every 28 days," said A. Berruti and colleagues, Azienda Osped San Luigi.

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Source: Cancer Weekly (2005-04-19)

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