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Acute Myeloid Leukemia

Criteria for defining complete remission re-evaluated

Published in Cancer Weekly, April 19th, 2005

The criteria for defining complete remission (CR) in acute myeloid leukemia (AML) have been re-evaluated.

In AML patients, CR "is the primary endpoint for the evaluation of induction treatment and treatment strategies," hematologists in the Netherlands explained.

"However, the choice and application of the criteria for a hematological CR can often become a subject of debate because regeneration of >5% blasts may be present at the time of response evaluation; platelet and neutrophil recovery may be incomplete and marrow cellularity can vary," noted G.E. de Greef and colleagues at the Erasmus Medical Center in Rotterdam.

In a...

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