Cancer Weekly
Susan Hasty, Publisher
Table of Contents . . . April 26th, 2005
Non-Subscriber - Summaries OnlyRelated Areas: Other Issues in Cancer Weekly | Other Publications
Cancer Therapy - Transcription factor 3 contributed to curcumin's proapoptotic effect
Carcinogenesis - Carcinogenicity of acrylamide explored
Cervical Cancer - Estrogen plays etiological role in HPV-transgenic mouse model
Follicular Thyroid Cancer - Expression profiling revealed transcription signature in thyroid carcinomas
Leukemia Vaccine - Multidrug resistance of leukemia cells decreases tumorigenicity
Acute Leukemia - ALL and AML have distinct methylation profiles
Acute Promyelocytic Leukemia - Sumoylation site in PML/RARA deemed essential for leukemic transformation
Addiction Medicine - Report finds kids of parents who use drugs prone to physical and mental illness
Adenocarcinoma - Appearance of supravesicular mass revealed urachal adenocarcinoma
Adverse Drug Reaction - Companies update TYSABRI safety review
Anemia - Erythropoietin advised only for symptomatic anemia
Cancer Vaccines - Recent findings in cancer vaccines described
Anesthesiology - Conscious sedation preferred for outpatient surgery
Apoptosis - Bovine leukemia virus involved in induction and inhibition of apoptosis
Apoptosis - Cancer cell apoptosis induced via Apo2L/TRAIL
Apoptosis - Heterogeneity of radiation-induced apoptosis in Ewing tumor cells characterized
Apoptosis - Intracellular overproduction of apolipoprotein L6 induced apoptosis
Apoptosis - Peripheral-type benzodiazepine receptor ligands amplified neuronal apoptosis
Cancer Vaccines - Research in cancer vaccines provides new insights
Apoptosis - Resveratrol regulated PKC alpha and delta to inhibit growth and induce apoptosis
Apoptosis - Survival of growth factor-deprived cells reported
Apoptosis - Zinc studied, effects on gene expression in embryonic cells revealed
Awards - Twenty-five scientists share $2.3 million in awards for prostate cancer research
Biomedical Engineering - MR images trace the path of genetically engineered natural killer cells
Bladder Cancer - Cylooxygenase-2 overexpression encourages tumor growth in murine bladders
Cervical Cancer - New findings in the area of cervical cancer detailed
Bone Cancer - Cryoablation treatment helps diminish pain of bone cancer
Bone Cancer - Herceptin and taxol may be effective combination therapy for Ewing sarcoma
Brain Cancer - Double-platinum chemotherapy with etoposide treated metastatic brain tumor
Brain Cancer - Metronomic methotrexate and cyclophosphamide don't stop recurrent glioblastoma
Brain Development - CNTF/LIF/gp130 receptor complex involved in developing ventral forebrain
Brain Ischemia - Cytidine 5'-diphosphocholine involved in stroke and other CNS disorders
Cervical Cancer - Recent findings in cervical cancer described
Breast Cancer - Advances refocus attention on prophylactic mastectomy
Breast Cancer - BI-RADS lexicon for U.S. helps differentiate benign from malignant solid masses
Breast Cancer - Bone SPECT superior to FDG PET for detecting bone metastases
Breast Cancer - Development of new screening system will continue
Breast Cancer - Environmental estrogens on [Ca2+]i in human breast cancer cells studied
Breast Cancer - Extracellular matrix plays key role in metastasis
Oncology - Findings advance knowledge in oncology research
Breast Cancer - Extracellular matrix protein collagen VI can modulate tumor behavior
Breast Cancer - Glucocorticoid receptor activation protects tumor cells via MAPK inhibition
Breast Cancer - HRT dose may be related to risk of disease recurrence
Breast Cancer - Intraoperative frozen sections of axillary lymph nodes in breast cancer examined
Breast Cancer - Lipid profiling recommended before and after hormonal therapy
Breast Cancer - MTHFR 677T variant/low folate associated with increased risk of breast cancer
Oncology - Findings in oncology provide new insights
Breast Cancer - NuMA gene variants associated with increased susceptibility
Breast Cancer - PKC delta and MAPK mediate G(1) arrest induced by PMA in SKBR-3 breast cancer
Breast Cancer - Researchers publish new studies and findings in the area of breast cancer
Breast Cancer - Twist and Wnt genes are highly expressed in breast cancer
Breast Cancer - Usefulness of routine preoperative lymphoscintigraphy questioned
Breast Cancer Research - Copper and zinc induced apoptosis in breast cancer cells
Oncology - New findings in oncology described
Breast Cancer Risk Factors - CHEK2 1100delC allele frequency is low in breast cancer families
Breast Cancer Therapy - Single-agent trastuzumab show promise for breast cancer
Breast Cancer Treatment - Paclitaxel containing less Cremophor EL as first-line therapy for breast cancer
Breast Cancer Vaccine - Structural consequences of increasing repeats in MUC1 tumor antigen reported
Breast Cancer Vaccines - Research add new data to breast cancer vaccines body of knowledge
Breast Tumors - Malignant tumors found accidentally during reduction mammaplasty
Oncology - Recent findings in oncology described
Business Update - Diagnostic testing company expands distribution network to Central America
Business Update - Medical device company selects investor relations firm
Business Update - New Japanese company set to be strong in neurology and cardiovascular disease
Business Update - Rapid flow-through diagnostic tech. provider upgrades system to ISO standard
Cancer Cachexia - Effect of cancer cachexia on the activity of tripeptidyl-peptidase II measured
Cancer Cell Apoptosis - Tumor cells sensitized to apoptosis by selective inhibition of specific Akt/PKB
Oncology - Recent findings in oncology provide new insights
Cancer Cell Inhibitors - (5R)-thiolactomycin used to develop new inhibitors of type I fatty acid synthase
Cancer Cell Inhibitors - Novel inhibitors of human histone deacetylases discovered
Cancer Cell Morphogenesis - Tetraspanin CD82 attenuated cellular morphogenesis
Cancer Cell Survival - H-RAS and K-RAS associated with cell survival
Cancer Diagnosis - Clonal abnormalities in Philadelphia-positive ALL and CML analyzed
Cancer Drugs - Effect of novel spirohydantoin derivatives on cancer cells evaluated
Oncology - Reports add new data to oncology research
Cancer Drugs - Extravascular transport of drugs in tumor tissue examined
Cancer Drugs - Hsp90 and Cdc37 nominated as possible cancer drugs
Cancer Immunotherapy - Combinations of monoclonal antibodies limit tumorigenesis
Cancer Immunotherapy - Fusion protein fights cervical cancer in murine models
Cancer Metastasis - The portal vein is vital for cancer cell trafficking to the liver
Cancer Prodrugs - Formaldehyde and butyric acid exhibited anticancer activity
Oncology - Research add new data to oncology body of knowledge
Cancer Radiotherapy - Therapy with radioisotopes in oncology discussed
Cancer Research - Armstrong seeks cyclists for Tour of Hope team to support cancer research
Cancer Research - Flavonoid in strawberries, other fruits, destroys cancer cells, study shows
Cancer Research - Progress and gaps in the understanding of transformation in cancer reported
Cancer Research - Spatially distinct binding of Cdc42 to key effector proteins studied
Cancer Research - Therapeutics company offers regulatory update on Cerepro and Vitor
Oncology - Researchers report details of new studies and findings in the area of oncology
Cancer Risks - Fanconi anemia led to increased cancer risk
Cancer Risks - HLA polymorphisms associated with H. pylori-infected gastric cancer
Cancer Risks - Reduction of E2F/DP activity might increase risk of cancer
Cancer Survival - Increase in S100A4 associated with decrease in cancer survival
Cancer Therapy - Antidepressant chlorimipramine reported to kill human glioma cells in vitro
Cancer Therapy - Antitumor activity of measles virus studied
Oncology - Researchers' findings advance oncology research
Cancer Therapy - Findings describe new data in cancer therapy research
Cancer Therapy - First two patients enrolled in phase II trial for AVR118
Cancer Therapy - Genetic testing could bolster radiotherapy's effectiveness against cancer
Cancer Therapy - Group awards grants for asbestos-related cancer
Cancer Therapy - Human MUC1 oncoprotein regulated p53-responsive gene transcription
Cancer Therapy - Novel mechanism of checkpoint abrogation conferred by Chk1 downregulation
Cancer Therapy - Phytosphingosine enhances apoptotic cell death
Cancer Therapy - Salicylate thwarts carcinogenesis and angiogenesis in mammary tumor studies
Cancer Therapy - Silatecan DB-67 showed promise in treating cancer
Cancer Therapy - TNF-alpha as a therapeutic agent
Cancer Therapy - Thiotepa inhibits cyclophosphamide metabolism
Cancer Therapy - Type XV collagen may be associated with tumorigenesis
Cancer Therapy - Viagra prevents anticancer drug-induced heart damage
Cancer Vaccine - DNA vaccine-induced lymphoma protection dependent on anti-idiotype antibodies
Cancer Vaccine - General cancer vaccine that targets survivin developed
Cancer Vaccine - Majority of women accept cervical cancer vaccine for self, children, study shows
Cancer Vaccine - Mass spectrometry used to detect specific MHC class I peptide antigens
Cancer Vaccine - Monocyte-derived dendritic cells present malignant glioma tumor cell lysates
Cancer Vaccine - N-modified GM3 antigens synthesized as therapeutic cancer vaccines
Cancer Vaccines - New research in the area of cancer vaccines detailed
Cancer-Related Pain - Cancer-related bone pain in children studied
Carcinogens - DNA damage and adduct formation in rat tissues after acrylamide administration
Cell Biology - Pair of cancer genes found to drive both cell migration and division
Cell Biology - Rictor-mTOR complex may be drug target
Cervical Cancer - Discriminatory abilities of apparent diffusion coefficient measurements studied
Cervical Cancer - Killer cell immunoglobulin-like receptor population affects disease risk
Cervical Cancer - Loss of Net as repressor led to increased c-fos transcription in cervical cancer
Cervical Cancer - New findings in the area of cervical cancer described
Chemotherapy - Epoetin alfa for treatment of cancer-related anemia reviewed
Chemotherapy - Mitotic spindle checkpoints targeted in topoisomerase-based chemotherapy
Chondrosarcoma - Tumor cell apoptosis induced by novel PPARgamma agonist characterized
Clinical Trials - Initial data from clinical trial of anticancer agent in leukemia repored
Clinical Trials - Therapeutics company announces that phase I trial of CS-917 is continuing
Collaborations - Agreement signed for Recaf cancer technology
Collaborations - Alliance to study antibody ARH460-16-2 in new disease indication
Collaborations - Biopharmaceutical manufacturer collaborates to develop oral vaccination
Collaborations - Partnership works toward increasing medicine access in poor countries
Collaborations - Research collaboration with International AIDS Vaccine Initiative announced
Colon Cancer - 15-Hydroxyprostaglandin dehydrogenase levels decline in colorectal cancer
Colon Cancer - Cytokine gene transfer halts the growth of colon cancer cells
Colon Cancer - DKK-1 gene expression in human colon tumors seen to decrease
Colon Cancer - Galectin-4 bound to sulfated glycosphingolipids and carcinoembryonic antigen
Colon Cancer - H-RAS V 12 and K-RAS D13 regulated radiation-induced signaling pathway function
Colon Cancer - New insights used for redefining the subcellular location and transport of APC
Colon Cancer - Predictors of atrial fibrillation after elective surgery for colorectal cancer
Colorectal Cancer - Abnormal p53 increases risk of death in colorectal cancer
Colorectal Cancer - Beta-catenin and APOE SNPs associated with positive family history of cancer
Colorectal Cancer - Mutations in TGFBR2 and BAX in neoplastic progression and patient outcome
Colorectal Cancer - Myricetin inhibited enzyme activity in colorectal carcinoma cells
Colorectal Cancer - Promoter methylation downregulates CDX2 expression in colorectal carcinomas
DNA Binding - Combinatorial identification of the covalent DNA-binding polyamide tallimustine
DNA Research - Nucleotide sequence variation found often in mitochondrial DNA of tumor cells
DNA Tumor Viruses - Hope placed in DNA tumor viruses to help understand cancer cell programming
Dermatology - Antisense oligodeoxynucleotide G3139 activates melanoma cell apoptosis
Diagnostics - Breast carcinoma: Persistent ITC in marrow suggests greater chance of recurrence
Diagnostics - DHPLC superior to SSCP in screening p53 mutations in esophageal cancer tissues
Diagnostics - Normal values of serum S-100B predict survival for melanoma patients
Diagnostics - Optimized liver biopsies permit routine microarray analyses of hepatitis C
Diagnostics - SELDI-TOF mass spectrometry profiles cancer risk in patients with hepatitis C
Disease Associations - H. pylori infection led to intestinal atrophy, metaplasia and gastric cancer
Disease Associations - Xeroderma pigmentosum skin reconstructed to study genetic hyperphotosensitivity
Drug Delivery - Cell-specific systems improve drug and gene delivery
Drug Delivery - Dimeric RGD peptide-paclitaxel conjugate abates tumor proliferation
Drug Development - Assay kit for kinase and phosphatase development introduced
Drug Development - Company's first cancer drug candidate moves toward clinical trials
Drug Development - Discovery Partners ink collaboration for lead identification on multiple targets
Drug Development - Fumigillin derivative CKD-732 is safe at presumed clinical doses
Drug Development - New research in the area of drug development detailed
Drug Development - Surgical and diagnostic products company submits amended IND application
Drug Resistance - Flavonoid BCRP inhibitors don't affect topotecan pharmacokinetics in rat model
Drug Resistance - Intercellular transfer of P-glycoprotein mediated multidrug resistance in tumors
Endocervical Adenocarcinomas - Metastatic tumors can appear to be ovarian surface epithelial neoplasms
Endocrinology - Fibroblast growth factor receptor is a target for thyroid cancer therapy
Endometrial Cancer - Binary system combining FIGO grades 1 and 2 results is highly reproducible
Endometrial Cancer - Endometrial cancer in African-American women is more aggressive, studies show
Enzymology - Matrix metalloprotease-1 uses protease-activated receptor to trigger metastasis
Enzymology - Neutral endopeptidase 24.11 stems ovarian cancer progression
Epstein-Barr Virus - PSK and Trx80 inhibit EBV-induced B-cell proliferation
Esophageal Cancer - Defective mismatch-repair linked to Barrett esophagus-associated adenocarcinoma
Finance - Cancer-focused pharmaceutical company reports Q4, full year 2004 results
Finance - German-American biotech company reports financial results
Finance - Imaging company completes $10.5 million private placement transaction
Finance - Maker of vaccines for cancer, AIDS reports increased revenues for Q4 and year
Finance - Oncology company reports loss of $0.06 per share
Finance - Pharmaceutical firm reports loss of $0.04 per share
Finance - Photoselective medicine company announces financial results
Gap Junctions - Novel GAP-like protein examined, influence on connexin revealed
Gastric Cancer - Lysophospholipids transactivate HER2/neu (ErbB-2) in gastric cancer cells
Gastritis - Inflammation from too little stomach acid leads to gastric cancer
Gastroenterology - Antiangiogenic therapies may prevent hyperplastic colorectal polyps
Gastroenterology - Studies describe new findings in gastroenterology research
Gender Medicine - Sex-specific gene profiles help personalize hepatitis C-related cancer therapy
Gene Research - DNA probes dissect the genetics of B-cell chronic lymphocytic leukemia
Gene Transfer - Combined gene therapy regimens demolish cancer proliferation
Genetics and Genomics - Gene expression during mouse colon embryonic development characterized
Ghrelin - Ghrelin studied, involvement in cell proliferation clarified
Gynecologic Cancer - Cervical and vulvar carcinomas share similar genetic abnormalities
Gynecology - New findings in the area of gynecology detailed
HIV/AIDS Research - Pharma company submits two new filings of antiretrovirals to WHO
HIV/AIDS Vaccines - Stanford study finds HIV drug resistance assay superior to Virco's Antivirogram
HIV/AIDS-Related Burkitt Lymphoma - Burkitt's lymphoma treated successfully concomitant with TB therapy and HAART
HTLV-1 - HTLV-1 HBZ suppresses AP-1 activity by impairing DNA-binding/c-Jun stability
Head and Neck Cancer - Cdc42/Rac1 involved in controlling telomerase activity in nasopharyngeal cancer
Head and Neck Cancer - Eight-year survival of head and neck cancer patients with human papillomaviruses
Head and Neck Cancer - Epstein-Barr virus-specific T lymphocytes treat nasopharyngeal cancer
Head and Neck Cancer - Small interfering RNA disrupts DNA methyltransferase and stops cancer growth
Head and Neck Surgery - Novel computer-guided scanner improves laser-assisted microincision
Health Promotion - Diagnostics company funds cervical cancer awareness campaign
Hematology - ABO blood group expression in oral carcinomas studied
Hematology - Anti-hepatitis C therapy drives natural killer-cell leukemia into remission
Hematology - Modified natural killer cells destroy acute myeloid leukemia cells
Hepatocellular Carcinoma - The p19ARF peptide may have use in treatment
Human Papillomavirus - Vaccine against virus causing cervical cancer and genital warts shows promise
Hypnosis - Efficacy of hypnosis and the neurophysiology of conversion disorder reviewed
Imaging - Swedish hospitals in Kalmar, Oskarshamn, Vostervik to get mammography systems
Imaging - U.S. FDA issues approvable letter for Combidex
Imaging - Winthrop-University Hospital to install clinical IT and imaging technologies
Immunology - Inactivation of proximal TCR signaling impairs T-cell-mediated tumor lysis
Immunology - Scientists shed new light on role of natural killer T cells in fighting disease
Infection Control - Antiseptic-coated CVCs reduce catheter infections in neutropenic patients
Information Technology - Foundation offers new Web resource on HIV/AIDS, TB and malaria
Information Technology - eclipboard check-in technology offers financial rewards, improves efficiency
Invasive Fungal Infection - RT panfungal PCR detects early invasive fungal infection in cancer patients
Kaposi Sarcoma-Associated Herpes Virus - HHV-8-infected SCs enhance immunostimulatory function of dendritic cell progeny
Kidney Cancer - Cystic renal neoplasia occurred after inactivation of tumor suppressor gene
Leukemia - Case of pancreatitis during leukemia treatment reported
Leukemia - ENT1 downregulation underlies Ara-C resistance
Leukemia - Genetically modified natural killer immune cells attack, kill leukemia cells
Leukemia - IFI16 identified as essential mediator of growth inhibition, not differentiation
Leukemia - Non-ATP-competitive inhibitor of BCR-ABL overrode imatinib resistance
Leukemia - Uncoupling protein 2 and reactive oxygen species characterized
Leukemia Vaccine - Protein kinase blockade stops change of myeloid blasts into dendritic cells
Liposarcoma - Liposarcoma subtypes identified with computed tomography and needle biopsy
Liver Cancer - Alpha-1,3-fucosyltransferase-VII stimulated growth of hepatocarcinoma
Liver Cancer - Chemoembolization and antiangiogenesis therapy stifle liver tumor growth
Liver Cancer - First-line treatment for inoperable liver cancer offers nonsurgical alternative
Liver Cancer - Living-donor liver transplant recommended for advanced hepatocellular cancer
Liver Cancer - Tamponade led to death after radiofrequency ablation of liver carcinoma
Liver Cancer - p53 absence promotes metastasis in mouse model of hepatocellular carcinoma
Liver Cancer Diagnostics - Different techniques for detecting hepatocellular carcinoma compared
Liver Cancer Diagnostics - Efficacy of T2-weighted magnetic resonance imaging in detecting hepatic tumors
Liver Disease - Yersinia enterocolitica infection in patient with hemochromatosis diagnosed
Lung Cancer - Carcinogen-specific dosimetry model for passive smokers of various ages revealed
Lung Cancer - Major vault protein does not play a role in chemoresistance or drug localization
Lung Cancer - Multiple developmental genes on chromosome 1p involved in lung tumorigenesis
Lung Cancer - Nonsurgical lung cancer treatment has 91% survival at 2 years
Lung Cancer - Oral supplementation of piperine altered phase II enzymes and reduced DNA damage
Lung Cancer - Overexpressed soluble TRAIL initiates the destruction of lung adenocarcinoma
Lymphoma - APl2-MALT1 fusion protein implicated in t(11;18)(Q21;q21) MALT lymphoma
Lymphoma Vaccine - Rapid expression of vaccine proteins for B-cell lymphoma developed
Malignant Mesothelioma - Treatment for malignant mesothelioma granted orphan status in Australia
Medical Devices - U.S. FDA grants clearance for treatment table with 550-pound load capacity
Melanoma - Hepatocyte growth factor induced fibronectin matrix synthesis in melanoma cells
Melanoma - MHC class II molecule activity in melanoma reported
Melanoma - Melanoma patients with 6p or 1q gains associated with lower survival rate
Melanoma - Peptide recognized by autologous cytolytic T lymphocytes on melanoma cells
Melanoma - Rac-WAVE2 involved in invasive and metastatic phenotypes of murine melanoma
Melanoma - UV exposure, genetic targets in melanocytic tumors, and transgenic mouse models
Melanoma Vaccine - Invasive melanoma cells induce metalloproteinase synthesis in fibroblasts
Melanoma Vaccine - Polyvalent melanoma vaccines elicit heterogeneous antibody responses
Melanoma Vaccines - Reports advance knowledge in melanoma vaccines research
Mergers & Acquisitions - Acquisition of Research Diagnostics Inc by biotech company completed
Mergers & Acquisitions - Siemens to acquire imaging company with focus on PET, other imaging technologies
Mesothelioma - SV40 not implicated in lung cancer
Metastasis - New technique finds molecules necessary for cancer spread
Morbid Obesity - Midabdominal TRAM flap used for breast reconstruction in morbid obesity
Motoneurons - Neurotrophic factors maintained motoneuron function
Mucosal Melanoma - Early diagnosis required for malignant melanoma of the uvula and soft palate
Mutagenic Indicators - Reaction-kinetic parameters of glycidamide determined mutagenic potency
Mycobacteria - Non-MTB mycobacteria not present in erythema induratum/nodular vasculitis
Myelodysplastic Syndrome - Findings describe new data in myelodysplastic syndrome research
Myelodysplastic Syndrome - Myelodysplastic syndrome resulted after temozolomide treatment for glioma
Myeloma - Association applauds VELCADE approval
Myeloma - U.S. DOD awards $1.6 million contract to develop bone-targeting nanocapsules
Natural Products - The flavonoid nobiletin reduces the metastatic potential of colon cancer
Neuroblastoma - Altered cell cycle gene expression marks aggressive tumors
Neuroscience - Subcellular localization of APC protein determined in developing neurons
Nicotine Addiction - Consumers not getting accurate information about smokeless tobacco
Non-Small Cell Lung Cancer - Pharma company reports on in vitro tests demonstrating PhG-alpha1
Oncogenesis - Green tea extract modulates actin remodeling via Rho activity
Oncogenesis - New findings in the area of oncogenesis detailed
Oncogenesis - Oncogenic K-RAS required to maintain changes in colon cancer cells
Oncology - Black bean tannins shut down angiogenic protein production in cancer cells
Oncology - COX-2 inhibition restores tumor suppressor activity in prostate cancer cells
Oncology - Chimeric enhancer controls adenovirus-based prostate cancer gene therapy
Oncology - Cytokeritin-7 delineates micrometastasis risk in patients with breast cancer
Oncology - Data advance knowledge in oncology research
Oncology - Decoy receptor 3 enhances monocyte adhesion to endothelial cells
Oncology - Demethylating agents augment antitumor immunotherapy
Oncology - Effects of p53 activation on healthy and tumor cells clarified
Oncology - Glucose deprivation-induced cytotoxicity and oxidative stress in cancer cells
Oncology - Hepatitis C infection spurs liver cancer growth by blocking apoptosis
Oncology - Neuropeptide Y supports the growth and vascularization of neuroendocrine tumors
Oncology - Silenced insulin-like growth factor binding protein-5 restricts neuroblastoma
Oncology - Specific cancers prevail in Swedish patients infected with hepatitis C
Oncology - Suppressed 6A8 alpha-mannosidase gene expression shortens cancer cell telomeres
Oral Cancer - Cyclin D1 polymorphism associated with increased susceptibility to oral cancer
Osteoporosis - Data show postmenopausal women in hormone study increased bone density
Ovarian Cancer - Inhibin resistance is associated with cancer cells' aggressive tumorigenicity
Ovarian Cancer - Src inhibition enhanced paclitaxel cytotoxicity in ovarian cancer cells
Ovarian Cancer - U.S. FDA accepts IND for treatment of advanced ovarian cancer with MORAb-003
Pancreatic Cancer - Chronic pancreatitis and associations with pancreatic adenocarcinoma examined
Pancreatic Cancer - PanIN, IPMNs, and MCNs are three precursors to invasive pancreatic cancer
Patents - Company gets patent for its selective chemotherapy treatment, NQO2
Patents - European patent granted for MCC in bladder cancer
Patents - European, Canadian allowances granted for anticancer drug in phase 2 trials
Pediatric Lymphoma - Genes cooperate to provoke immune system cancer B-cell lymphomas, study shows
Pediatric Oncology - Genetic signatures define pediatric osteosarcoma
Pediatrics - FDA approves ZOFRAN for use in children as young as 1 month of age
Peripheral Arterial Disease - First drug-eluting stent implant for leg artery blockage performed at Stanford
Personnel - Madhusudan V. Peshwa, PhD, named VP, R&D by clinical stage therapeutics company
Personnel - Molecular diagnostics company names Paul Gobeil as chairman of the board
Personnel - Pharma company appoints chairman of the board of directors
Phosphatase - Oncoprotein 1-2(PP2A)/SET examined, negative regulatory activity documented
Product Licensing - Pharma companies enter license agreement for ProMune
Prostate Cancer - Advanced cancer previously considered inoperable may be operable, curable
Prostate Cancer - Biotech company announces results from prostate cancer study
Prostate Cancer - Combined treatment approach increases survival in prostate cancer
Prostate Cancer - Company confirms success of HIFU with Ablatherm
Prostate Cancer - Composition and histone substrates of polycomb repressive complexes changed
Prostate Cancer - MR-guided biopsies in patients with suspected prostate cancer reviewed
Prostate Cancer - Magmas expression linked to neoplastic human prostate
Prostate Cancer - Nonsurgical cryoablation, "male lumpectomy" preserves function
Prostate Cancer - TNP-470 and docetaxel synergize to abolish prostate cancer
Prostate Cancer - Tumor-reactive TGF-beta-insensitive CD8+ T cells target prostate malignancies
Protein Kinase - Protein kinase C signaling examined, role as a survival pathway revealed
Proteomics - Adapter protein Tks5/Fish needed for podosome formation and cancer cell invasion
Proteomics - Hepatitis C virus core protein mediates cellular response to TRAIL
Pulmonary Medicine - Lymphangiogenesis predicts poor survival in neuroendocrine lung tumor patients
Reconstructive Surgery - Scarring at free radial forearm flap donor site is manageable
Rectal Cancer - Phase II study of S-1 plus irinotecan in advanced colorectal cancer patients
Skin Cancer - Cancer can be characterized by microarrays
Skin Cancer - Chronic UVB exposure drives clonal expansion by a nonmutational mechanism
Skin Cancer - Increased apoptosis led to decreased skin cancer in UV-irradiated CD1d-/- mice
Skin Cancer - Protein kinase C epsilon signaled ultraviolet light-induced skin cancer
Skin Cancer - Researchers test new therapy for advanced melanoma
Skin Cancer - The role of tumor-stroma interactions in carcinogenesis examined
Skin Cancer Prevention - Ultraviolet-B radiation damage prevented in mouse skin
Stem Cell Research - ESCs require signaling through PI 3-kinase pathway to suppress apoptosis
Stem Cell Research - Mesenchymal stem cells modulate allogeneic immune cell responses
Stem Cell Research - P53 induces differentiation of ESCs by suppressing Nanog expression
Stem Cell Transplantation - New data illuminates research in stem cell transplantation
Stem Cell Transplantation - RIST regimen for nonmalignant disorders reduces risk of GVHD
Stem Cell Transplantation - Younger age/days of apheresis/male gender predict increased yield of CD34+ cells
Stomach Cancer Risk Factors - Stomach cancer risk not associated with exposure to radon or other radionuclides
Surgical Technology - Alabama hospital treating patients with new Trilogy stereotactic system
Syndecan - Syndecan analyzed, invasion regulatory domain identified
T-Cell Leukemia - PKC theta mediates pre-TCR signaling/adds to Notch3-induced T-cell leukemia
Targeting Tumor Growth - Scientists identify novel anticancer target
Testicular Cancer - Imatinib mesylate stops malignant Leydig cell tumor growth
Tissue Engineering - Organic-inorganic hybrid scaffold used to culture hepatocellular carcinoma cells
Tobacco Use - Pharma company welcomes news of Medicare coverage of smoking cessation
Tobacco Use - Smokers believe medicinal nicotine products may be harmful, study shows
Tumor Suppression - Role of PP2A as tumor suppressor inspected
Tumorigenesis - Liver receptor homolog 1 contributed to intestinal tumor formation
Tumorigenesis - PPARgamma inhibited tumorigenesis in metastatic non-small cell lung cancer cells
Vaccines - Prostaglandin E2 enhances intestinal adenoma growth
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