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Biopharmaceutical manufacturer collaborates to develop oral vaccination

Published in Cancer Weekly, April 26th, 2005

Cobra Biomanufacturing plc (CBF) announced the results of a 5-year research collaboration with the U.K. Ministry of Defense agency, defense science and technology laboratory (dstl), in Porton Down, U.K., on the development of an improved approach to oral vaccination that avoids the risks of using antibiotics or antibiotic-resistance genes.

Comparison of the ORT-VAC system with conventional bacteria vaccine strains show that, post administration, the ORT VAC product is stable and the conventional strains highly unstable. In other experiments reported in the same paper, using a rigorous plague challenge model in rodents, proof-of-principle results published show that a...

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