Endocrinology

Fibroblast growth factor receptor is a target for thyroid cancer therapy

Published in Cancer Weekly, April 26th, 2005

Fibroblast growth factor receptor is a target for thyroid cancer therapy.

"Several molecular abnormalities of potential therapeutic target value have been described in thyroid neoplastic transition. We report the expression of the fibroblast growth factor receptor family (FGFR-1-4) in normal thyroid tissues, human thyroid cancers of various types and behaviors, and cell lines representative of the spectrum of differentiation of tumors derived from follicular epithelial cells," scientists writing in the journal Endocrinology stated.

"FGFR-2 was the only receptor consistently detected in normal human thyroid tissue, and its expression diminished...

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Source: Cancer Weekly (2005-04-26)

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