Cancer Vaccines

Research in cancer vaccines provides new insights

Published in Cancer Weekly, April 26th, 2005

Reports from the United States and Germany highlight recent research on cancer vaccines.

Study 1: Researchers report the results of a study on the role of tumor-derived exosomes in cancer-associated T-cell signaling defects in a recent issue of the British Journal of Cancer.

"Dendritic and lymphoid exosomes regulate immune activation. Tumors release membranous material mimicking these exosomes, resulting in deletion of reactive lymphocytes. Tumor-derived exosomes have recently been explored as vaccines, without analysis of their immunologic consequences. This investigation examines the composition of tumor-derived exosomes and their effects on...

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Source: Cancer Weekly (2005-04-26)

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