Hepatocellular Carcinoma
The p19ARF peptide may have use in treatment
Published in Cancer Weekly, April 26th, 2005
"Recent genetic studies demonstrate that mice deficient in the forkhead box m1b (Foxm1b) transcription factor are highly resistant to developing hepatocellular carcinoma, which is among the most lethal cancers worldwide," scientists in the United States explained.
"In addition, the Foxm1b transcription factor was identified as a novel inhibitory target of the p19ARF tumor suppressor during early stages of liver tumorigenesis, but p19ARF expression is extinguished in hepatic tumors that develop at later stages," noted R.H....
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Source: Cancer Weekly (2005-04-26)
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