Breast Cancer

HRT dose may be related to risk of disease recurrence

Published in Cancer Weekly, April 26th, 2005

The doses of estrogen and progestogen used in menopausal hormone therapy may be related to the risk of breast cancer recurrence, according to a new study.

In 1997, two randomized trials - the Hormonal Replacement Therapy - Is It Safe' (HABITS) trial and the Stockholm trial - began in Sweden to test the effects of menopausal hormone therapy in women after they had been diagnosed with early-stage breast cancer. The HABITS trial, which ultimately included 434 breast cancer patients, was halted early in December 2003 because at a median follow-up of only 2.1 years the risk of breast cancer recurrence among women receiving hormone therapy was 3.3 times higher than the risk...

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Source: Cancer Weekly (2005-04-26)

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