Cancer Therapy

Reports describe recent advances in cancer therapy research

Published in Cancer Weekly, May 3rd, 2005

Data on cancer therapy are outlined in reports from the United States and People's Republic of China.

Study 1: Doxazosin halts vascular endothelial cell adhesion, migration, and invasion.

"The quinazoline-derived alpha1-adrenoceptor antagonists doxazosin and terazosin have been recently shown to induce an anoikis effect in human prostate cancer cells and to suppress prostate tumor vascularity in clinical specimens [Keledjian and Kyprianou, 2003]. This study sought to examine the ability of doxazosin to affect the growth of human vascular endothelial cells and to modulate vascular endothelial growth factor (VEGF)-mediated angiogenesis," scientists in...

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Source: Cancer Weekly (2005-05-03)

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