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Diet & Nutrition

Soy isoflavone supplement has antioxidant, but not estrogenic, effect

Published in Cancer Weekly, May 10th, 2005

Dietary supplementation with soy isoflavone was shown in a study to have beneficial antioxidant effects in postmenopausal breast cancer survivors, but not estrogenic effects associated with higher disease risk.

Ohio State University scientists wrote, "Soy isoflavone antioxidant effects may help prevent breast cancer reoccurrence, but isoflavone estrogen-like actions may increase breast cancer risk. These isoflavone actions can be reflected by effects on two copper enzymes activities, superoxide dismutase 1 (SOD 1), which has antioxidant function relevant to breast cancer prevention, and ceruloplasmin, which has its synthesis upregulated by estrogen, and for which high...

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