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Oncogenesis

New findings in oncogenesis described

Published in Cancer Weekly, May 10th, 2005

Data on oncogenesis are outlined in reports from Germany, the United States and Japan.

Study 1: Smad4 changes are involved in the formation of cervical cancer.

"Squamous cell carcinoma of the uterine cervix is one of the most frequent cancers affecting women worldwide. Carcinomas arise from cervical intraepithelial lesions, in which infection with high-risk human papillomavirus types has led to deregulated growth control through the actions of the viral E6 and E7 oncoproteins. The molecular mechanisms underlying progression to invasive tumor growth are poorly understood," scientists writing in the journal Oncogene report.

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