Published in Cancer Weekly, May 10th, 2005
"An N-linked glycan often increased during oncogenic transformation contains beta(1,6)-linked GlcNAc, synthesized by GnTV. The progression of polyoma middle T-antigen oncoprotein-induced mammary carcinomas in GnTV-null mice was significantly retarded compared with that observed in wild-type mice. The matrix adhesion of mouse embryonic fibroblasts (MEF) from GnTV-null and wild-type mice was...
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