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Breast Cancer

BRCA1/2 germline mutations evaluated in breast cancer moderate/low-risk persons

Published in Cancer Weekly, May 10th, 2005

BRCA1 and BRCA2 germline mutations were evaluated in breast cancer moderate- and low-risk persons.

According to recent research from Greece, "The current study was designed to evaluate the prevalence of BRCA1 and BRCA2 germline mutations in Greek moderate- and low-risk individuals with respect to clinicopathological phenotype and clinical outcome of breast cancer.

"Ninety-four consecutive individuals were prospectively recruited from two University Breast Cancer Clinics (Hippokrateion Hospital and Laikon Hospital) between 1989 and 1999 and were categorized as moderate-risk and low-risk individuals for carrying BRCA1/2 germline mutations."

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