Vector Development

Gene-modified autologous cells chauffeur gene therapy to metastatic tumors

Published in Cancer Weekly, May 10th, 2005

Gene-modified autologous cells chauffeur gene therapy to metastatic tumors.

"A long-pursued goal in cancer treatment is to deliver a therapy specifically to metastases. As a result of the disseminated nature of the metastatic disease, carrying the therapeutic agent to the sites of tumor growth represents a major step for success. We hypothesized that tumor cells injected intravenously (i.v.) into an animal with metastases would respond to many of the factors driving the metastatic process, and would target metastases," scientists in Spain report.

"Using a model of spontaneous metastases, we report here that i.v. injected tumor cells localized on...

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Source: Cancer Weekly (2005-05-10)

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