Colorectal Cancer

DCC and p27(Kip1) do not predict survival in colorectal cancer patients

Published in Cancer Weekly, May 17th, 2005

The colorectal cancer gene DCC and p27(Kip1) do not predict survival in colorectal cancer patients.

"The progression of colorectal cancer is a multistage process associated with specific molecular alterations. The stepwise accumulation of these multiple genetic mutations progressively results in the acquisition of neoplastic cell behavior. The genetic abnormalities associated with the expression of metastatic phenotype, therefore, may be of prognostic significance in the clinical treatment of colorectal cancer patients," scientists in the United States reported in a study published in Applied Immunohistochemistry & Molecular Morphology.

"In...

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Source: Cancer Weekly (2005-05-17)

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