HIV/AIDS Research
KIR epitope expression may influence NK-mediated immune response in HIV/AIDS
Published in Cancer Weekly, May 17th, 2005
"The Killer Ig-like receptors (KIRs) on NK cells regulate NK activity via the recognition of specific HLA class I products on the surface of target cells," scientists in Australia report.
"To investigate the level at which these genetically polymorphic receptors and ligands influence HIV-1 disease progression," wrote S. Gaudieri and colleagues at the Royal Perth Hospital, "we examined the effect of KIR and HLA genotype on HIV outcome."
The authors concluded, "We observed a significant association between particular combinations...
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Source: Cancer Weekly (2005-05-17)
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