Tamoxifen
Molecular changes associated with agonist activity of hydroxy-tamoxifen
Published in Cancer Weekly, May 24th, 2005
"The aim of this study was to explore the pharmacological response to OH-Tam and to E-2 in three cell lines: MVLN, a human breast carcinoma cell line derived from MCF-7, and two MVLN-derived OH-Tam-resistant (OTR) cell lines, called CL6.8 and CL6.32," scientists writing in the journal Endocrine-Related Cancer reported.
"The OH-Tam response in the OTR cells was associated with the development of both an agonist activity of the drug on cell proliferation and the resistance of the cells to...
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Source: Cancer Weekly (2005-05-24)
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