Cancer Therapy

Data reported in study of doxorubicin in PLGA-based microparticles

Published in Cancer Weekly, May 31st, 2005

Data has been reported from an in vitro study of anticancer drug doxorubicin in PLGA-based microparticles.

According to recent research published in the journal Biomaterials, "Doxorubicin (DOX), also known as adriamycin, is an anthracycline drug commonly used in cancer chemotherapy. Unfortunately, its therapeutic potential has been restricted by its dose-limited cardiotoxicity and the resistance developed by the tumor cells to the molecule after some time of treatment. One way to overcome these problems is to encapsulate the drug in poly (D, L-lactide-co-glycolide) (PLGA) microparticles."

"This paper investigates the release characteristics of...

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Source: Cancer Weekly (2005-05-31)

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