Genetics & Genomics
Genetic alterations implicated in accelerated aging syndromes
Published in Cancer Weekly, May 31st, 2005
According to a study from Poland, "The molecular mechanisms leading to human senescence are still not known mostly because of the complexity of the process. Different research approaches are used to study aging including studies of monogenic segmental progeroid syndromes. None of the known progerias represents true precocious aging."
"Some of them, including Werner (WS), Bloom (BS), and Rothmund-Thomson syndromes (RTS) as well as combined xeroderma pigmentosa-Cockayne syndrome (XP-CS) are characterized by features resembling precocious aging and the increased risk of malignant...
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Source: Cancer Weekly (2005-05-31)
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