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Radioprotectors

Amifostine used as radioprotector of salivary glands in radioiodine therapy

Published in Cancer Weekly, June 14th, 2005

Scientists claimed amifostine could be used as a radioprotector of salivary glands during radioiodine therapy.

"Salivary gland impairment following high-dose radioiodine treatment is well recognized. Since differentiated thyroid cancer has a good prognosis, reduction of long-term side effects is important," researchers in Germany reported.

"This study investigates the radioprotective effects of amifostine in salivary glands of rabbits receiving high-dose radioiodine therapy so as to obtain deeper insight in changes on the cellular and ultrastructural level. A total of 20 rabbits were investigated," explained H. Kutta and colleagues, University...

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