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Melanoma

Genasense phase III results in malignant melanoma updated at ASCO

Published in Cancer Weekly, June 21st, 2005

Genta, Inc., (GNTA) announced long-term follow-up results from the company's phase III trial of Genasense (oblimersen sodium) Injection in patients with advanced malignant melanoma.

Earlier analyses showed that the addition of Genasense to chemotherapy yielded a statistically significant increase in overall response, complete response, and time-to-progression. Extended follow-up for a minimum of 24 months in all patients has revealed that patients treated with Genasense also achieved a significant increase in "durable" response (i.e., responses longer than 6 months duration) (p=0.02) and a near-significant trend toward increased overall survival (p=0.077).

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