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Endothelial Growth Factor

Endothelial growth factor receptor studied, link with ovarian carcinoma shown

Published in Cancer Weekly, June 28th, 2005

A study from Italy has reported on the correlation of epidermal growth factor receptor (EGFR) expression with tumor microdensity vessels and with vascular endothelial growth factor (VEGF) expression in ovarian carcinoma.

"We analyzed in advanced ovarian serous G3 carcinoma the correlation between EGFR overexpression and tumor angiogenesis and their relation with clinical outcome," wrote M.R. Raspollini and colleagues, University of Florence.

"Microvessel density (MVD) and VEGF were statistically correlated with disease-free interval and death from disease both in univariate and multivariate analyses while EGFR expression was not correlated with...

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