Immunotherapy
Piceatannol may be used in DC-based vaccine for cancer immunotherapy
Published in Cancer Weekly, June 28th, 2005
"Piceatannol is an anti-inflammatory, immunomodulatory, and antiproliferative stilbene that has been shown to interfere with the cytokine signaling pathway. Dendritic cells (DCs) play a pivotal in the initiation of T-cell-mediated immune responses, making them an attractive cellular adjuvant for use in cancer vaccines," M. Takei and colleagues recently reported in the Journal of Pharmaceutical Sciences.
"This study investigated the effect of piceatannol on the phenotypic and functional maturation of human monocyte-derived DCs in vitro. Human monocytes were cultured with...
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Source: Cancer Weekly (2005-06-28)
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