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Acute Myeloid Leukemia

Results of clofarabine trial in adult AML presented at conference

Published in Cancer Weekly, July 5th, 2005

Bioenvision (BIVNE) announced that results from clinical trials of clofarabine in adult acute myeloid leukemia (AML) were presented at the 10th European Hematology Association (EHA) meeting in Stockholm, Sweden.

In the National Cancer Research Institute, U.K. (NCRI) multicenter study of older patients with AML who were unsuitable for intensive chemotherapy, the overall response for clofarabine was 67%. Eleven (42%) patients in this trial had abnormal cytogenetics, and of these five (45%) achieved a complete response (CR) with clofarabine. For patients with normal cytogenetic profile, the CR was 73%. In addition, the median duration of remission in patients responding to...

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