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Oncology

Reports describe recent advances in oncology research

Published in Cancer Weekly, July 12th, 2005

Data on oncology are outlined in reports from Canada and the United States.

Study 1: Clusterin inhibition enhances prostate cancer's response to primary therapy.

According to a study from Canada, "the discovery and targeting of genes mediating androgen-independence may lead to the development of novel therapies that delay progression of hormone refractory prostate cancer (HRPC). Clusterin is a stress-associated cell survival gene that increases after androgen ablation."

"Here, we review clusterin's functional role in apoptosis and the use of antisense oligonucleotides (ASOs) against clusterin to enhance apoptosis in prostate...

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